Trust & Compliance

Clinical AI must be explainable, permission-aware, and reviewable.

HIPAA
GDPR
GxP Validation
ISO 9001
21 CFR Part 11
Annex 11
SOC 2
ISO27001
ISO42001

Powerful AI is not enough for clinical trials.

Clinical trial data is among the most regulated and consequential data on the planet. It informs regulatory submissions, product safety decisions, and patient care. The AI layer over that data carries the same burden. Vivo is designed for this standard, not just described as compliant with it.

Source-backed answers Role & blinding-aware Human review built in Governed automation Continuous AI evaluation
Security & Privacy

Built for clinical-grade data handling.

Vivo handles de-identified and identified clinical trial data in compliance with HIPAA and GDPR. Data residency, access controls, encryption at rest and in transit, and audit logging are standard, not optional.

  • HIPAA compliance for protected health information
  • GDPR compliance for EU/EEA subject data
  • Encryption at rest and in transit (TLS 1.2+, AES-256)
  • Data residency controls for global trials
  • Penetration testing and vulnerability management
  • Single sign-on (SSO) and MFA enforcement
  • Zero data retention by LLM providers for Vivo API calls
Compliance & Standards

Aligned with the standards that govern clinical AI.

GxP Validation Framework
Risk-based validation approach aligned with intended use. GMP, GCP, and GDP-aligned quality system.
21 CFR Part 11 / Annex 11
Electronic records, electronic signatures, and audit trails for validated clinical software systems.
ISO 9001
Quality Management System (QMS) certification covering product development and delivery.
SOC 2 Type II / ISO27001
Security, availability, and confidentiality audit currently in progress.
ISO42001
Artificial Intelligence Management System (AIMS) certification covering the responsible use of AI.
Access Control

Role-based and blinding-aware — enforced at the data layer.

Every user interacts with a Vivo that reflects their role, function, and study assignment. A medical monitor sees different data than a data manager. A sponsor sees different data than a CRO site coordinator. And in active trials, blinding integrity is enforced at the platform level — not just in the UI.

  • Role-based access control (RBAC) — configurable per study and organization
  • Blinding-aware data access — treatment arm, dose group, and endpoint data protected
  • Ask Vivo answers are role-aware — the AI cannot return data the user should not see
  • Sponsor, CRO, and site access scoped independently
  • Access logs, session records, and permission changes audited

Role-Aware Access Example

Medical Monitor
Full safety data view · AEs, labs, SAEs, dose · Blinding-aware · Evidence packages
Data Manager
EDC, labs, queries, review state, completeness · No treatment arm data
ClinOps / Study Lead
Enrollment, sites, vendors, operational status · Trial Home · Protocol adherence
Portfolio Leader
Cross-study risk view · Portfolio Ask Vivo · Executive reporting scope

Source-Backed Answers & Audit Trails

Every Vivo answer, alert, and insight links back to the specific source records, transformation steps, and protocol context that support it. You can trace from conclusion to evidence in two clicks. Every answer, query, and workflow action is timestamped, attributed, and preserved.

"Trust does not come from confidence. Trust comes from traceability."

Human Review & Governed Automation

AI in Vivo assists clinical teams — it does not replace them. Alerts, issues, and monitoring outputs are reviewed by humans before action. Governed workflows include reviewer comments, decision attribution, resolution records, and complete audit trails. AI signals the risk. People own the response.

Signal Evidence Review Action Audit

Exploratory vs. Confirmatory Workflows

Vivo draws a clear distinction between exploratory and confirmatory use. Ask Vivo is designed for operational insight and monitoring — not for pre-specified statistical analysis or hypothesis confirmation. Clinical AI should accelerate insight without weakening scientific discipline.

Exploratory use (operational) and confirmatory use (statistical analysis) are governed separately.

Prompt & Usage Monitoring

Governed AI includes governing how AI is used. Vivo monitors usage patterns across studies for anomalous queries, blinding-adjacent questions, cross-arm comparisons in active trials, and usage that may affect study integrity. This is a proactive safety layer, not just an audit log.

Validation

Validation is not one-size-fits-all. It should follow intended use.

Vivo supports sponsor validation programs with documentation, risk assessments, testing artifacts, and implementation guides aligned with FDA CSA guidance and GxP quality frameworks.

What OmniScience Provides

  • Quality Management System (ISO 9001)
  • Change control and release management
  • Risk-based validation documentation
  • System description and IQ/OQ/PQ support materials
  • Audit trail and electronic record documentation
  • Vendor qualification support package

What Sponsor Teams Do

  • Sponsor validation protocol and report
  • Risk and intended use classification
  • User acceptance testing (UAT)
  • Internal SOP alignment and training records
  • Study-specific configuration documentation
  • Periodic review and requalification
Enterprise & Procurement Readiness

Ready for every stakeholder in the evaluation process.

IT & Security Teams

  • SSO / SAML / SCIM integration
  • MFA enforcement
  • Data residency options
  • Penetration test artifacts
  • Vendor security questionnaire support
  • SOC 2 bridge letter available

QA & Compliance Teams

  • Vendor qualification package
  • Validation support documentation
  • QMS overview (ISO 9001)
  • Audit trail and 21 CFR Part 11 documentation
  • Change control and release notes
  • On-site audit support

Enterprise AI / Innovation Teams

  • API documentation and sandbox access
  • LLM provider and model governance details
  • AI evaluation methodology
  • Data handling and zero-retention confirmation
  • Agent interoperability and API contracts

Ready for a vendor assessment?

Our team provides detailed documentation, qualification materials, and questionnaire support.