Vivo Platform

One governed operating layer for clinical trial execution.

Vivo brings together trial data, AI reasoning, continuous monitoring, evidence generation, and workflow action so teams can understand status, detect risk, and coordinate response across studies and portfolios.

The Operating Layer

From fragmented trial data to coordinated clinical action.

Clinical trials generate more data than ever, but most study teams still manage execution through disconnected systems, vendor portals, CRO reports, spreadsheets, and periodic status updates. That creates a gap between when data is collected and when teams can act on it. Vivo closes that gap.

Unified live trial data Source-backed AI reasoning Continuous monitoring Evidence → action Portfolio scale
Capability 1

Unified Clinical Trial Data Layer

Vivo ingests, harmonizes, and monitors structured and semi-structured trial data across systems. Every source remains traceable. Cross-domain review becomes possible across subjects, sites, visits, endpoints, labs, adverse events, vendors, and documents.

Supported source categories:

EDCCTMSTMF / eTMFSafety / PVCentral LabsImagingeCOA / ePROIRT / RTSMWearables / DHTsBiomarkersOmicsVendor FilesCRO ReportsSponsor Warehouses

"A clinical trial is not one system. Vivo gives teams one operating picture."

Integration approach

API Integration
Real-time / near-real-time refresh where available (Medidata RAVE, PPD, Veeva, etc.)
Batch / File Ingestion
Scheduled file processing: CSV, XML, SAS, CDISC ODM, JSON, flat files
Read-Only Source Integrity
Vivo never modifies source data. Source systems remain the system of record.
AI-Assisted Ingest Code
AI generates and validates data mapping code to accelerate onboarding

Trial Home — Daily View

Trial status: On track. 3 items need attention.
Site 104: Enrollment 40% behind plan — 18 days no screenings
Safety signal: AE cluster at Site 104 (Cohort B) — review recommended
CRO Vendor B: Lab data refresh overdue by 3 days
12 other items unchanged since last review
Last updated: 4 hours ago · Next refresh in 2h
Capability 2

Trial Home

Trial Home gives study teams a continuously updated view of what is happening across the trial, what changed since the last review, what needs attention, and what actions are pending. Designed for the rhythm of real clinical development work.

  • Current status across enrollment, sites, vendors, data quality, safety, and protocol
  • What changed since the last review cycle
  • Emerging risks that require attention
  • Open alerts, issues, assignments, and review items
  • Trial News summaries for cross-functional teams

"Know what changed before the meeting starts."

Capability 3

Ask Vivo — Governed Clinical Trial AI

Ask Vivo gives clinical development teams a governed AI interface to their own trial data, documents, protocol context, and operating workflows. Not a chatbot — a source-backed reasoning layer designed for clinical use.

  • Plain-language questions over live trial data and documents
  • Protocol and amendment question answering
  • Role-aware — every answer reflects your permissions
  • Source-backed explanations with evidence citations
  • Visual outputs, summaries, and generated tables

"Ask the trial. See the evidence."

Ask Vivo
Data Management
Which subjects have missing data for critical endpoint visits in domains flagged for lock readiness?
Answer
14 subjects have incomplete data for ≥1 critical endpoint visit. 9 are in the primary endpoint domain (ADAS-Cog). Sites 211 and 308 account for 11 of the 14. 3 subjects have records that changed after their last review date.
↗ Source: EDC completeness module · DM review state · Lab data · Last refreshed 1h ago
Portfolio
Which studies have the highest execution risk this month across our oncology portfolio?
Answer
Study OS-204 has the highest composite risk: enrollment 18% behind plan, 2 site activations overdue, and 1 vendor data lag flag. Study OS-107 shows rising protocol deviation rate over 4 weeks (+22%).
↗ Source: Portfolio dashboard · CTMS milestone data · Site performance module
Capability 4

Continuous Monitoring — AI-RBQM

A signal is only valuable if the right team sees it, understands it, and acts on it. Vivo continuously monitors trial data and turns signals into governed action.

Detect

Continuously watch for missing, late, inconsistent, unexpected, or high-risk patterns across all connected sources.

Alert

Generate governed alerts with source evidence and affected entities. Share across the team. Set thresholds from protocols or Ask Vivo prompts.

Act

Convert alerts to issues. Assign ownership. Track resolution. Preserve evidence packages for audit, inspection, and review.

Vivo monitors for risk across:

Missing or delayed data
Cross-system discrepancies
Enrollment & screen failure trends
Site & vendor performance drift
Visit adherence & retention risk
Protocol deviations
Safety & medical review signals
Endpoint readiness
Lock-readiness blockers
Capability 5

Portfolio Intelligence

Vivo helps clinical development leaders move beyond study-by-study updates into portfolio-level intelligence. See where attention is needed, then drill into the study, site, subject, vendor, or data domain driving the issue.

  • Which studies carry the highest execution risk
  • Which sites or vendors are creating issues across programs
  • Which trials show worsening data quality trends
  • Which milestones are under pressure
  • What changed across the portfolio since the last review

"One study creates clarity. A portfolio creates operating leverage."

Portfolio Risk View

Study OS-204 · Oncology Phase 2 High Risk
Study CNS-107 · Alzheimer's Phase 2 Medium Risk
Study IMM-033 · I&I Phase 3 On Track
Study RD-019 · Rare Disease Phase 2 On Track
4 active studies · 2 need attention · Last updated 3h ago
Differentiation

Not a dashboard. Not a chatbot. Not another silo.

Dashboards show what happened.

Vivo explains what changed and what action should follow.

Chatbots answer questions.

Vivo monitors the trial and connects answers to source-backed workflows.

Data warehouses store data.

Vivo helps clinical teams interpret, prioritize, and act on data.

RBQM tools identify risk.

Vivo connects risk to evidence, issues, review workflows, and portfolio context.

"Our CMO went from spending a week plus manually collating and creating the various tables he wanted for DSMB to maybe 30, 45 minutes. That's just transformative to how we do business."

VP, Clinical Operations · Alzheimer's Disease Global Phase 2 Trial

Bring trial data, AI reasoning, monitoring, and action into one governed layer.

Vivo helps clinical development teams understand what changed, detect risk earlier, ask better questions, and coordinate response with source-backed evidence.